ECCO 2019: Transcriptional profiling of ulcerative colitis in remission

Ruth Paulssen | ECCO 2019 | MAALISKUU 11, 2019

Asiantuntija: Ruth Paulssen

This study addresses whether existing transcriptional profile scan improve and support the current definition of UC in remission apart from the today existing endoscopic, histological and laboratory scoring systems.

Ruth Paulssen propose in the MEDtalk that a gut–brain communication network is involved during remission beside the partial restoration of immunological functions and recovery of local homeostasis in the epithelial mucus layer and lamina propria. In addition, a certain role for the composition of bacterial gut flora may be implied.